Scientist I
Sanofi

Job Title: Scientist I

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress.

Global Discovery Pathology and Multimodal Imaging (GDPMI) team based in Cambridge, MA is committed to delivering project-focused solutions for all Sanofi research projects by providing integrated expertise in translational/comparative pathobiology, specialized histology, and innovative cellular, molecular and ex vivo/in vivo imaging through our agile, empowered, and collaborative team. We are looking for a highly motivated and enthusiastic Scientist (Histotechnology and Molecular Pathology) to join our team. If you are passionate about working with transversal teams, maintaining high performance standards in a fast-paced and scientifically driven environment, working independently and contributing to the discovery and development of novel therapeutics for patients, this is a position for you.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people's lives. We're also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities:

• Independently perform histological work including tissue trimming, processing, embedding, sectioning, and staining for preclinical and research projects, following laboratory SOPs.
  
• Work closely with pathologists, scientists, and management to execute approved procedure for individual projects and accurately document newly implemented protocols.
  
• Run automated tissue processors, autostainer and perform digital whole slide scanning, perform routine lab inspections, quality control of equipment and processes, and diligently troubleshoot technical operational issues.
  
• Provide histology support for molecular assays (IHC, IF, ISH) and spatial technologies.
  
• Communicate with internal and external collaborators to manage prioritization, timelines, samples collection, accurate registration and tracking in our LIMS.
  
• Provide study progress through active communication using our department project management tool.
  
• Support laboratory operations and outsourcing.
  

About You

Requirements:

• Master's Degree plus minimum 3 years of relevant research experience in an academic or biopharmaceutical setting OR Bachelor's Degree plus minimum 6 years of relevant research experience in an academic or biopharmaceutical setting.
  
• Certification in histotechnology (HTL) is preferred.
  
• Demonstrated knowledge of modern histology laboratory workflow including automated processing, staining, slide scanning and laboratory information management system (LIMS) and familiarity with digital pathology applications such as HALO, Visiopharm etc...
  
• Hands on experience in handling fixed laboratory animal tissue specimens, sectioning (FFPE and frozen) and expertise in tissue microarray (TMA) technology
  
• Experience in necropsy assistance and tissue sampling in rodent model in-vivo studies.
  
• Outstanding communication and interpersonal skills and willingness to work with matrixed teams in a diverse, collaborative and fast paced environment.
  
• Ability to adapt to the constantly evolving portfolio priorities.
  
• Excellent organizational skills.
  

Preferred qualifications:

• Familiarity with brightfield tissue slide scanning (Aperio).
  
• Experience with automated and/or manual tissue-based molecular assays (IHC, IF and ISH).
  
• Experience with histology workflow for spatial platforms preferred.
  
• Previous histology experience working with microphysiological systems is a plus.
  
• Vibratome sectioning experience.
  

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.
  
• Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
  
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
  
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
  

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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